Company

nanoLiter LLC, a Henderson, NV LLC, was founded five years ago by Mr. Andrew D. Sauter Jr. and his son Andrew D. Sauter III, EE. Nanoliter OEM's/sells nanoliter products,fluidic integration services and contract R&D. in conjunction with core partners in California and three other partner companies.We offer affordable IBF nanoLiter Cool Wave® dispensers and technology, and related consulting. nanoLiter LLC also offers licenses for MS sample handling, sample introduction and other applications on an OEM basis. IBF has other powerful applications too, like making charged matter and polymers and even cooling human beings as we demonstrated for the US Army. Please contact us with questions.

Drew Sauter is a physical organic analytical chemist (MS Marquette and BS Duquesne U in Chemistry) with expertise in MS, fluidics, numerics and analytical chemistry, in particular, quantitative mass spectrometry. He has published in signal processing, pattern recognition, national data base building, on EI, CI and ESI fundamentals, in applied and basic GC, LC/MS and MS/MS. He has written complete business plans, patents and given numerous invited papers and presentations at labs and conferences from Los Alamos to ECBC to WMI. He’s been sole source procured as an expert in MS and analytical chemistry by seven different branches of the US government and he has consulted with most MS firms. He teaches a course on IBF and nanoLiter sample handling at Pittcon every year.

Drew invented and developed GC/MS technology, multivariate QC and contracts that have been used to characterize the environment and the water drank in the USA for the last 35 years. Implementation aspects of federal environmental laws are based on his papers. This work included solving the GC/MS interface problem with HP’s invention of FCSS. In that area, he first published three interlaboratory studies, as the leader of a number of teams, inventing and proving the technology for the largest MS program ever, Superfund. He purchased Dr. Robert Finnigan’s first triple quadrupole mass spectrometer and reported the first ever LC/MS/MS high throughput screening at ASMS and in the literature in 1983. He directed federal funding to Dr. Sam Houk, the inventor of ICP/MS, and acquired funding for Extrel and Willoughby for early LC/MS technology that was eventually purchased by Waters, that being their entrée into mass spectrometry. He wrote a fundamental paper on how to predict EI GC/MS response factors and he later developed data capture and analysis programs for $M contract he won at Los Alamos.

In the 90’s after reading 600 papers on ESI, he performed a few simple experiments in his garage that formed the basis of induction based fluidics, a technology that was called “elegant” by the former Director of R&D at Sciex, Dr. Willliam Davidson with an offer to license. Recent comments by some of the most senior MS scientist have called IBF MALDI data published by users as “astounding.” Furthermore, in 2011 at ASMS, we showed that one can shoot 100% of ambient temperature liquid samples into MS’s and IMS’s !!! This will, we predict, result in a major (50 to 1000x) increase in MS and MS/MS reproducibility across the board. This work and the resulting ability to shoot samples of cell fragments(!!!), 100% of the sample, into different ESI/MS and MS/MS systems was characterized as “exciting” by America's greatest mass spectroscopists. Drew Sauter now claims via IBF to have solved for all time, the MS liquid introduction problem, as he solved the GC/MS interface problem in 1980. IBF technology can be seen on YouTube (http://www.youtube.com/adsauterjr) dispensing 100% of liquids into MS systems in milliseconds or dispensing in parallel (from dispensers, SPE's or from LC columns) 384 channels in one millisecond, the fastest in the world. Users of IBF technology include: U’s of Illinois, California and Wisconsin, USU, USF, Duquesne, NIH, NIST, US Army at ECBE, Biogen Idec, Genentech, Allergan, Tetracore, Hitachi to name a few.

Nanoliter "owns" the future of simple laboratory liquid handling deivce, as we delibreately appended and patented IBF applied to microliter syringes, pipettes, pumps, chips, SPE devices and more which we sell and seek to license. Those very successful products can now become non-touch uL or nL dispensers for countless applications that inclued a nanoliter pipette and syringe tip.

Also, we invented and patented an IBF embodiment to allow for 100% sample introduction to MS's, MS/MS's, IMS's and other intstruments which we sell and which we also seek to license for MALDI, LC/MALDI, tissue MALDI sample prep, LDI, SIMS, DART, DESI and 100% nL MS sample preparation technology. The same technogy can be used in making electrets, charged polymers, features for fluidic devices and more. We are also seeking other commercialization partners, distribution channels and reps.